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KMID : 0602819960020010103
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Korean Journal of Bronchoesophagology
1996 Volume.2 No. 1 p.103 ~ p.110
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Diagnostic and Therapeutic Analysis of Globus Pharyngeus
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홍원표
김은서/김동영/김지수/최홍식/김영덕
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Abstract
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Globus pharyngeus is a common problem comprising between 3% and 4% of new
otolaryngology outpatient referrals. We do not understand the etiology of globus exactly and
it is remained a disease of exclusion. The treatment of glous pharyngeus is stillnot
established.
The aim of this study is to understand the etiologic factors and determine the reliable reliable
guide for selecting method of choice of evaluation and improving therapeutic response of
glovus pharyngeus. Atotal of 141 patients wereinvestigated by authors. 24 fo 141 patients
were excluded from the study because they could not satisfy the definition criteria of this
sutdy After detailed interview and comprehensive physical exminations, all the 116 patients
had underwent barium esophagogram, fiberoptic esophagogastroscopy, esophageal manometry
and 24-hour pH monitoring. They could follow up for at least 3 months.
There were 43 male and 73 female subjects and the mean age was 46.5 year. Esophagogram
revealed normal in 94(81%) subjects. 78 patients(67.2%) were normal in esophageal
manometry. Gastroesophageal reflux(GERD) was found in 24 cases and borderline GERD was
found in 25 cases showing an overall incidence of 42.2% for 24-hour pH monitoring.
Especially 44(89.8%) of the 49 patients with proven reflux on 24-hour pH monitoring showed
therapeutic response whereas 48(71.6%) of the 67 subjects without reflux showed response.
In recognizing the etiologic factors, barium esophagogram is less diagnostic but important role
in excluding other organic causes. however, Esophagel manometry together with 24-hour pH
monitoring may be important in selecting treatment increasing therapeutic responses.
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KEYWORD
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